The BSSI team includes biostatisticians, statistical geneticists and IT specialists working together to provide comprehensive and efficient solutions to your biomarker analysis needs. Whether we assist in your initial PGx Study Design or join your team during the process, BSSI can execute the complex statistical analyses required to answer your study objectives.

Our services include:

• Genome-wide and candidate gene association studies
• Genotypic quality control
• Haplotype analysis
• Combination marker analysis
• Copy number variation analysis
• Gene x gene and gene x environment interactions
• Gene expression analysis
• Population stratification
• Multiple comparison adjustment
• Power and sample size evaluation

We have extensive experience with complex study designs:

• Categorical and quantitative traits
• Case / control and family-based studies
• Compound designs
• Limited and substantial sample sizes
• Univariate and multivariate analysis
• Pharmacokinetics and pharmacodynamics

We have expertise in a wide-range of biostatistics methods. For more information on how our PGx analyses on clinical trials are conducted in accordance with FDA and EMEA guidelines, please see more information about our Regulatory Compliances.

Contact us for more information about these and other capabilities.